BMY-7,378

BMY-7,378
(IUPAC) ime
	8-(2-[4-(2-metoksifenil)-1-piperazinil]etil)-8-azaspiro[4.5]dekan-7,9-dion
Klinički podaci
Identifikatori
CAS broj	21102-95-4
ATC kod	nije dodeljen
PubChem	2419
ChemSpider	2325
Hemijski podaci
Formula	C22H31N3O3
Mol. masa	385,499 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C22H31N3O3/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22/h2-3,6-7H,4-5,8-17H2,1H3 ; Key: AYYCFGDXLUPJAQ-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

BMY-7,378 je parcijalni agonist/antagonist 5-HT_1A receptora i antagonist α_1D-adrenergičkog receptora.^[4]

Reference[uredi | uredi kod]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Goetz AS, King HK, Ward SD, True TA, Rimele TJ, Saussy DL (January 1995). „BMY 7378 is a selective antagonist of the D subtype of alpha 1-adrenoceptors”. European Journal of Pharmacology 272 (2-3): R5–6. DOI:10.1016/0014-2999(94)00751-R. PMID 7713154.

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