Astacin

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Astacin
PDB 1qjj EBI.jpg
Identifikatori
EC broj 3.4.24.21
CAS broj 143179-21-9
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Astacin (EC 3.4.24.21, Astacus proteinaza) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

Hidroliza peptidnih veza u supstratima koji sadrže pet ili više aminokiselina, preferentno sa Ala u P1', i Pro u P2'

Ova endopeptidaza varenja je prisutna u rakovima Astacus fluviatilis.

Reference[uredi - уреди]

  1. Krauhs, E., Dörsam, H., Little, M., Zwilling, R. and Ponstingl, H. (1982). "A protease from Astacus fluviatilis as an aid in protein sequencing". Anal. Biochem. 119: 153–157. PMID 7041692. 
  2. Titani, K., Torff, H.-J., Hormel, S., Kumar, S., Walsh, K.A., Rödl, J., Neurath, H. and Zwilling, R. (1987). "Amino acid sequence of a unique protease from the crayfish Astacus fluviatilis". Biochemistry 26: 222–226. PMID 3548817. 
  3. Stöcker, W., Wolz, R.L., Zwilling, R., Strydom, D.J. and Auld, D.S. (1988). "Astacus protease, a zinc metalloenzyme". Biochemistry 27: 5026–5032. 
  4. Stöcker, W., Ng, M. and Auld, D.S. (1990). "Fluorescent oligopeptide substrates for kinetic characterization of the specificity of Astacus protease". Biochemistry 29: 10418–10425. PMID 2261483. 

Literatura[uredi - уреди]

Vanjske veze[uredi - уреди]