Aminoacilaza
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| Aminoacilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.1.14 | ||||||||
| CAS broj | 9012-37-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Aminoacilaza (EC 3.5.1.14, dehidropeptidaza II, histozim, hipurikaza, benzamidaza, acilaza I, hipuraza, amidokiselinska deacilaza, L-aminoacilaza, acilaza, aminoacilaza I, L-aminokiselinska acilaza, alfa-N-acilaminokiselinska hidrolaza, dugoacilna amidoacilaza, kratkoacilna amidoacilaza) je enzim sa sistematskim imenom N-acil-L-amino-kiselina amidohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- N-acil-L-aminokiselina + H2O karboksilat + L-aminokiselina
Ovaj enzim ima široku specifičnost. On takođe hidrolizuje dehidropeptide.
Reference[uredi | uredi kod]
- ↑ Birnbaum, S.M., Levintow, L., Kingsley, R.B. and Greenstein, J.P. (1952). „Specificity of amino acid acylases”. J. Biol. Chem. 194: 455-470. PMID 14927637.
- ↑ Fones, W.S. and Lee, M. (1953). „Hydrolysis of N-acyl derivatives of alanine and phenylalanine by acylase I and carboxypeptidase”. J. Biol. Chem. 201: 847-856. PMID 13061423.
- ↑ Park, R.W. and Fox, S.W. (1960). „An acylase system related to the utilization of benzoylamino acids by Lactobacillus arabinosus”. J. Biol. Chem. 235: 3193-3197. PMID 13732833.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.