Alkilacetilglicerofosfataza
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| Alkilacetilglicerofosfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.3.59 | ||||||||
| CAS broj | 102925-45-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Alkilacetilglicerofosfataza (EC 3.1.3.59, 1-alkil-2-lizo-sn-glicero-3-P:acetil-KoA acetiltransferaza, alkilacetilglicerofosfatna fosfataza) je enzim sa sistematskim imenom 1-alkil-2-acetil-sn-glicero-3-fosfat fosfohidrolaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 1-alkil-2-acetil-sn-glicero-3-fosfat + H2O 1-alkil-2-acetil-sn-glicerol + fosfat
Ovaj enzim učestvuje u biosintezi trombocit aktivirajućeg faktora u životinjskim tkivima.
Reference[uredi | uredi kod]
- ↑ Lee, T.-C., Malone, B. and Snyder, F. (1986). „A new de novo pathway for the formation of 1-alkyl-2-acetyl-sn-glycerols, precursors of platelet activating factor. Biochemical characterization of 1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase in rat spleen”. J. Biol. Chem. 261: 5373-5377. PMID 3007498.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.