ATPaza spajanja vezikula
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| ATPaza spajanja vezikula | |||||||||
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| Heksamer NSF (= N-etilmaleimid senzitivni faktor) (Cricetulus griseus) | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.6.4.6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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ATPaza spajanja vezikula (EC 3.6.4.6) je enzim sa sistematskim imenom ATP fosfohidrolaza (fuzija vezikula).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ova velika familija ATP-hidrolizujućih enzima učestvuje u heterotipnoj fuziji membranskih vezikula sa ciljnim membranama i homotipnu fuzuju raznim membranskih kompartmana.
Reference[uredi | uredi kod]
- ↑ Confalonieri, F. and Duguet, M. (1995). „A 200-amino acid ATPase module in search of a basic function”. BioEssays 17: 639-650. PMID 7646486.
- ↑ Imamura, A., Tamura, S., Shimoyawa, N., Suzuki, Y., Zhang, Z., Tsukamoto, T., Orii, T., Kondo, N., Osumi, T. and Fujiki, Y. (1998). „Temperature-sensitive mutation in PEX1 moderates the phenotypes of peroxisome deficiency disorders”. Hum. Mol. Genet. 7: 2089-2094. PMID 9817926.
- ↑ Babst, W., Wendland, B., Estepa, E.J. and Emr, S.D. (1998). „The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function”. EMBO J. 17: 2982-2983. PMID 9606181.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.