5-Benziloksitriptamin

5-Benziloksitriptamin
(IUPAC) ime
	2-(5-phenylmethoxy-1H-indol-3-yl)ethanamine
Klinički podaci
Identifikatori
CAS broj	20776-45-8
ATC kod	?
PubChem	89576
ChemSpider	80845
Hemijski podaci
Formula	C17H18N2O
Mol. masa	266.34 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C17H18N2O/c18-9-8-14-11-19-17-7-6-15(10-16(14)17)20-12-13-4-2-1-3-5-13/h1-7,10-11,19H,8-9,12,18H2 ; Key: WKPDXBXNJWWWGQ-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

5-Benziloksitriptamin (5-BT) je derivat triptamina koji deluje kao agonist 5-HT_1D, 5-HT₂ i 5-HT₆ serotoninskih receptora.^[4]^[5]^[6]^[7]

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Literatura[uredi | uredi kod]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Lyon RA, Titeler M, Seggel MR, Glennon RA (January 1988). „Indolealkylamine analogs share 5-HT2 binding characteristics with phenylalkylamine hallucinogens”. European Journal of Pharmacology 145 (3): 291–7. DOI:10.1016/0014-2999(88)90432-3. PMID 3350047.
↑ Peroutka SJ, McCarthy BG, Guan XM (1991). „5-benzyloxytryptamine: a relatively selective 5-hydroxytryptamine 1D/1B agent”. Life Sciences 49 (6): 409–18. DOI:10.1016/0024-3205(91)90582-V. PMID 1650872.
↑ Cohen ML, Schenck K, Nelson D, Robertson DW (January 1992). „Sumatriptan and 5-benzyloxytryptamine: contractility of two 5-HT1D receptor ligands in canine saphenous veins”. European Journal of Pharmacology 211 (1): 43–6. DOI:10.1016/0014-2999(92)90260-B. PMID 1319907.
↑ Boess FG, Monsma FJ, Carolo C, Meyer V, Rudler A, Zwingelstein C, Sleight AJ (1997). „Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells”. Neuropharmacology 36 (4-5): 713–20. DOI:10.1016/S0028-3908(97)00019-1. PMID 9225298.

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[pmid3350047-4] Lyon RA, Titeler M, Seggel MR, Glennon RA (January 1988). „Indolealkylamine analogs share 5-HT2 binding characteristics with phenylalkylamine hallucinogens”. European Journal of Pharmacology 145 (3): 291–7. DOI:10.1016/0014-2999(88)90432-3. PMID 3350047.

[pmid1650872-5] Peroutka SJ, McCarthy BG, Guan XM (1991). „5-benzyloxytryptamine: a relatively selective 5-hydroxytryptamine 1D/1B agent”. Life Sciences 49 (6): 409–18. DOI:10.1016/0024-3205(91)90582-V. PMID 1650872.

[pmid1319907-6] Cohen ML, Schenck K, Nelson D, Robertson DW (January 1992). „Sumatriptan and 5-benzyloxytryptamine: contractility of two 5-HT1D receptor ligands in canine saphenous veins”. European Journal of Pharmacology 211 (1): 43–6. DOI:10.1016/0014-2999(92)90260-B. PMID 1319907.

[pmid9225298-7] Boess FG, Monsma FJ, Carolo C, Meyer V, Rudler A, Zwingelstein C, Sleight AJ (1997). „Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells”. Neuropharmacology 36 (4-5): 713–20. DOI:10.1016/S0028-3908(97)00019-1. PMID 9225298.

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5-Benziloksitriptamin

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