4-Hlorobenzoil-KoA dehalogenaza
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4-Hlorobenzoil-KoA dehalogenaza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.8.1.7 | ||||||||
CAS broj | 141583-18-8 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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4-Hlorobenzoil-KoA dehalogenaza (EC 3.8.1.7) je enzim sa sistematskim imenom 4-hlorobenzoil KoA hlorohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 4-hlorobenzoil-KoA + H2O 4-hidroksibenzoil KoA + hlorid
Ovaj enzim je specifičan za dehalogenaciju u poziciji 4.
Reference[uredi | uredi kod]
- ↑ Chang, K.H., Liang, P.H., Beck, W., Scholten, J.D., Dunaway-Mariano, D. (1992). „Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3”. Biochemistry 31: 5605-5610. PMID 1610806.
- ↑ Crooks, G.P., Copley, S.D. (1994). „Purification and characterization of 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain 4-CB1”. Biochemistry, 33: 11645-11649. PMID 7918379.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.