2,6-Diokso-6-fenilheksa-3-enolatna hidrolaza
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| 2,6-Diokso-6-fenilheksa-3-enolatna hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.7.1.8 | ||||||||
| CAS broj | 102925-38-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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2,6-Diokso-6-fenilheksa-3-enolatna hidrolaza (EC 3.7.1.8, HOHPDA hidrolaza) je enzim sa sistematskim imenom 2,6-diokso-6-fenilheksa-3-enoat benzoilhidrolaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2,6-diokso-6-fenilheksa-3-enoat + H2O benzoat + 2-oksopent-4-enoat
Ovaj enzim odvaja produkte sa bifenola, 3-izopropilkatehola i 3-metilkatehola formirane enzimom EC 1.13.11.39, bifenil-2,3-diol 1,2-dioksigenazom.
Reference[uredi | uredi kod]
- ↑ Omori, T., Sugimura, K., Ishigooka, H. and Minoda, Y. (1986). „Purification and some properties of a 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolyzing enzyme from Pseudomonas cruciviae S93 B1 involved in the degradation of biphenyl”. Agric. Biol. Chem. 50: 931-937.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.