14-Cinamoiloksikodeinon

14-Cinamoiloksikodeinon
(IUPAC) ime
	7,8-didehidro-4,5α-epoksi-14-cinamoil-3-metoksi-17-metilmorfinan-6-on
Klinički podaci
Identifikatori
CAS broj	751-01-9
ATC kod	nije dodeljen
PubChem	6438241
ChemSpider	4942728
Hemijski podaci
Formula	C27H25NO5
Mol. masa	443,490 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C27H25NO5/c1-28-15-14-26-23-18-9-10-20(31-2)24(23)32-25(26)19(29)12-13-27(26,21(28)16-18)33-22(30)11-8-17-6-4-3-5-7-17/h3-13,21,25H,14-16H2,1-2H3/b11-8+/t21-,25+,26+,27-/m1/s1 ; Key: BWZTYCFJIMYOHI-JKGZCERPSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

14-Cinamoiloksikodeinon je najpotentniji primer u seriji opijatnih analgetika. On je otkriven tokom 1960-tih i oko 100 puta je potentniji od morfina.^[4] On je derivat hidroksikodeinona, koji sadrži 14-cinamatni estar.^[5]

Reference[uredi | uredi kod]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Lien, E. J.; Tong, G. L.; Srulevitch, D. B.; Dias, C. (1978). „QSAR of Narcotic Analgetic Agents” (pdf). NIDA Research Monograph 1978 (22): 186–196. PMID 30907. Arhivirano iz originala na datum 2011-10-15. Pristupljeno 2014-04-05.
↑ Buckett, W. R. (1965). „Some Pharmacological Studies With 14-Cinnamoyloxycodeinone”. The Journal of Pharmacy and Pharmacology 17 (11): 759–760. PMID 4379812.

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Lien, E. J.; Tong, G. L.; Srulevitch, D. B.; Dias, C. (1978). „QSAR of Narcotic Analgetic Agents” (pdf). NIDA Research Monograph 1978 (22): 186–196. PMID 30907. Arhivirano iz originala na datum 2011-10-15. Pristupljeno 2014-04-05.

[pmid4379812-5] Buckett, W. R. (1965). „Some Pharmacological Studies With 14-Cinnamoyloxycodeinone”. The Journal of Pharmacy and Pharmacology 17 (11): 759–760. PMID 4379812.

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14-Cinamoiloksikodeinon

Reference[uredi | uredi kod]

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