1-Testosteron

Izvor: Wikipedia
1-Testosteron
(IUPAC) ime
(1S,2R,7S,10R,11S,14S,15S)-14-hidroksi-2,15-dimetiltetraciklo[8.7.0.0^{2,7}.0^{11,15}]heptadek-3-en-5-on
Klinički podaci
AHFS/Drugs.com Monografija
Identifikatori
CAS broj 65-06-5
ATC kod nije dodeljen
PubChem[1][2] 236666
DrugBank DB01481
ChemSpider[3] 206590
KEGG[4] C15377 YesY
Hemijski podaci
Formula C19H28O2 
Mol. masa 288.4244
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća  ?
Pravni status

Delta 1-dihidrotestosteron je anabolički steroid koji se razlikuje od testosterona po tome što ima 1,2-dvostruku vezu umesto 4,5-dvostruke veze u A prstenu.[5][6][7]

Reference[uredi - уреди]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. doi:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. doi:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. Joanne Wixon, Douglas Kell (2000). "Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG". Yeast 17 (1): 48–55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  5. Friedel A, Geyer H, Kamber M, Laudenbach-Leschowsky U, Schanzer W, Thevis M, Vollmer G, Zierau O, Diel P: 17beta-hydroxy-5alpha-androst-1-en-3-one (1-testosterone) is a potent androgen with anabolic properties. Toxicol Lett. 2006 Aug 20;165(2):149-55. Epub 2006 Apr 18. PMID 16621347
  6. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). "DrugBank 3.0: a comprehensive resource for omics research on drugs". Nucleic Acids Res. 39 (Database issue): D1035–41. PMID 21059682. 
  7. Nucleic Acids Res (2008). DrugBank: a knowledgebase for drugs, drug actions and drug targets 36 (Database issue). pp. D901–6. PMID 18048412. 

Spoljašnje veze[uredi - уреди]

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