1,8-Cineolna sintaza

Izvor: Wikipedia
1,8-Cineolna sintaza
Identifikatori
EC broj 4.2.3.108
CAS broj 110637-19-9
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

1,8-Cineolna sintaza (EC 4.2.3.108, 1,8-cineolna ciklaza, geranilna pirofoshat:1,8-cineolna ciklaza, 1,8-cineolna sintetaza) je enzim sa sistematskim imenom geranil-difosfat difosfat-lijaza (ciklizacija, formira 1,8-cineol).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju

geranil difosfat + H2O \rightleftharpoons 1,8-cineol + difosfat

Za dejstvo ovog enzima je neophodan jon Mn2+ ili Zn2+.

Reference[uredi - уреди]

  1. Croteau, R., Alonso, W.R., Koepp, A.E. and Johnson, M.A. (1994). "Biosynthesis of monoterpenes: partial purification, characterization, and mechanism of action of 1,8-cineole synthase". Arch. Biochem. Biophys. 309: 184–192. PMID 8117108. 
  2. Wise, M.L., Savage, T.J., Katahira, E. and Croteau, R. (1998). "Monoterpene synthases from common sage (Salvia officinalis). cDNA isolation, characterization, and functional expression of (+)-sabinene synthase, 1,8-cineole synthase, and (+)-bornyl diphosphate synthase". J. Biol. Chem. 273: 14891–14899. PMID 9614092. 
  3. Peters, R.J. and Croteau, R.B. (2003). "Alternative termination chemistries utilized by monoterpene cyclases: chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases". Arch. Biochem. Biophys. 417: 203–211. PMID 12941302. 
  4. Chen, F., Ro, D.K., Petri, J., Gershenzon, J., Bohlmann, J., Pichersky, E. and Tholl, D. (2004). "Characterization of a root-specific Arabidopsis terpene synthase responsible for the formation of the volatile monoterpene 1,8-cineole". Plant Physiol. 135: 1956–1966. PMID 15299125. 
  5. Keszei, A., Brubaker, C.L., Carter, R., Kollner, T., Degenhardt, J. and Foley, W.J. (2010). "Functional and evolutionary relationships between terpene synthases from Australian Myrtaceae". Phytochemistry 71: 844–852. PMID 20399476. 

Literatura[uredi - уреди]

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