(RS)-norkoklaurin 6-O-metiltransferaza
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| (RS)-norkoklaurin 6-O-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.128 | ||||||||
| CAS broj | 89700-33-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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(RS)-norkoklaurin 6-O-metiltransferaza (EC 2.1.1.128, (RS)-norcoclaurine 6-O-methyltransferase) je enzim sa sistematskim imenom S-adenozil-L-metionin:(RS)-norkoklaurin 6-O-metiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + (RS)-norkoklaurin S-adenozil-L-homocistein + (RS)-koklaurin
Ovaj enzim takođe katalizuje 6-O-metilaciju (RS)-norlaudanozolina do 6-O-metil-norlaudanozolina.
Reference[uredi | uredi kod]
- ↑ Rueffer, M., Nagakura, N., Zenk, M.H. (1983). „Partial purification and properties of S-adenosyl-L-methionine:(R),(S)-norlaudanosoline-6-O-methyltransferase from Argemone platyceras cell cultures”. Planta Med. 49: 131-137.
- ↑ Sato, F., Tsujita, T., Katagiri, Y., Yoshida, S. and Yamada, Y. (1994). „Purification and characterization of S-adenosyl-L-methionine:norcoclaurine 6-O-methyltransferase from cultured Coptis japonica cells”. Eur. J. Biochem. 225: 125-131. PMID 7925429.
- ↑ Stadler, R., Zenk, M.H. (1990). „A revision of the generally accepted pathway for the biosynthesis of the benzyltetrahydroisoquinoline reticuline”. Liebigs Ann. Chem.: 555-562.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.