(Acil-nosilac-protein) fosfodiestaraza
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| (acil-nosilac-protein) fosfodiestaraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.4.14 | ||||||||
| CAS broj | 37288-21-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
(acil-nosilac-protein) fosfodiestaraza (EC 3.1.4.14, ACP hidrolijaza, ACP fosfodiesteraza, AcpH, (acil-nosilac-protein) 4'-pantetein-fosfohidrolaza, holo-(acil-nosilac-protein) 4'-pantetein-fosfohidrolaza) je enzim sa sistematskim imenom holo-(acil-nosilac protein) 4'-pantetein-fosfohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- holo-[acil-nosilac protein] + H2O 4'-fosfopantetein + apo-[acil-nosilac protein]
Ovaj enzim razlaže acil-[acil-nosilac-protein] molekule sa acil lancima 6-16 ugljenika.
Reference[uredi | uredi kod]
- ↑ Sobhy, C. (1979). „Regulation of fatty acid synthetase activity. The 4′-phosphopantetheine hydrolase of rat liver”. J. Biol. Chem. 254: 8561-8566. PMID 224058.
- ↑ Vagelos, P.R. and Larrabee, A.R. (1967). „Acyl carrier protein. IX. Acyl carrier protein hydrolase”. J. Biol. Chem. 242: 1776-1781. PMID 4290442.
- ↑ Thomas, J. and Cronan, J.E. (2005). „The enigmatic acyl carrier protein phosphodiesterase of Escherichia coli: genetic and enzymological characterization”. J. Biol. Chem. 280: 34675-34683. PMID 16107329.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.