Šablon:PBB/1956

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Receptor epidermalnog faktora rasta

Extracellular domain of Epidermal growth factor receptor in complex with EGF. PDB 1nql[1]
Dostupne strukture
1IVO, 1M14, 1M17, 1MOX, 1NQL, 1XKK, 1YY9, 1Z9I, 2EB2, 2EB3, 2GS2, 2GS7, 2ITN, 2ITO, 2ITP, 2ITQ, 2ITT, 2ITU, 2ITV, 2ITW, 2ITX, 2ITY, 2ITZ, 2J5E, 2J5F, 2J6M, 2JIT, 2JIU, 2JIV, 2KS1, 2M0B, 2M20, 2RF9, 2RFD, 2RFE, 2RGP, 3B2U, 3B2V, 3BEL, 3BUO, 3C09, 3G5V, 3G5Y, 3GOP, 3GT8, 3IKA, 3LZB, 3NJP, 3OB2, 3OP0, 3P0Y, 3PFV, 3POZ, 3QWQ, 3UG1, 3UG2, 3VJN, 3VJO, 3VRP, 3VRR, 3W2O, 3W2P, 3W2Q, 3W2R, 3W2S, 3W32, 3W33, 4G5J, 4G5P, 4HJO, 4I1Z, 4I20, 4I21, 4I22, 4I23, 4I24, 4JQ7, 4JQ8, 4JR3, 4JRV, 4KRL, 4KRM, 4KRO, 4KRP, 4LI5, 4LL0
Identifikatori
Simboli EGFR; ERBB; ERBB1; HER1; PIG61; mENA
Vanjski ID OMIM131550 MGI95294 HomoloGene74545 GeneCards: EGFR Gene
EC broj 2.7.10.1
Pregled RNK izražavanja
PBB GE EGFR 201983 s at.png
podaci
Ortolozi
Vrsta Čovek Miš
Entrez 1956 13649
Ensembl ENSG00000146648 ENSMUSG00000020122
UniProt P00533 Q01279
RefSeq (mRNA) NM_005228 NM_007912
RefSeq (protein) NP_005219 NP_031938
Lokacija (UCSC) Chr 7:
55.09 - 55.32 Mb
Chr 11:
16.75 - 16.92 Mb
PubMed pretraga [1] [2]
  1. Ferguson Km, B. M.; Berger, M. B.; Mendrola, J. M.; Cho, H. S.; Leahy, D. J.; Lemmon, M. A. (2003). "EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization". Molecular Cell 11 (2): 507–517. doi:10.1016/S1097-2765(03)00047-9. PMID 12620237.  edit